JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

Anaemia

ObligatoryMust not donate if:
a) Mother or Father homozygous or heterozygous for inherited haemoglobin disorder or enzymopathy.

Inform Transplant Centre if:
b) Cells are from a baby that has an inherited disorder.
Discretionary1. a) If the cord blood is tested for the relevant condition and is shown to be unaffected, accept.

b) For X linked disorders, if father affected and male baby, accept. If mother affected and female baby, accept.

c) For non-X linked disorders, if baby heterozygous (trait), accept.

2. History of anaemia:
This should be assessed regarding its cause, current status and what treatment has been received.

3. Iron deficiency:
If not under investigation and the underlying cause is not a reason to exclude, accept.

4. Other types:
Accept or exclude according to the guidelines.

5. In other cases:
Refer to a Designated Medical Officer.
See if RelevantHaemoglobin Disorders
Haemolytic Anaemia
Malignancy

If treated with blood components or products or by plasma exchange or filtration:
Transfusion
Additional InformationA successful transplant will mean the recipient will produce the same blood as the donor. This would be unacceptable for a homozygous (major) form of blood disorder but would probably be acceptable for a heterozygous (minor form, or trait).

By informing the transplant centre, details can be passed on to the person receiving the transplant. This can avoid unnecessary problems in the future. For example searching for the cause of small red cells or anaemia in a person who has had a transplant from a donor with thalassaemia minor (trait).

Update Information

This entry was last updated in
TDSG-CB Edition 203, Release 02