If donor has undergone surgery for a benign adrenal tumour (adenoma), the donor is fully recovered, has been discharged from follow up and is not on medication for Conn’s syndrome, accept.
Conn’s syndrome (primary hyperaldosteronism) is caused by overproduction of aldosterone in the adrenal cortex. Aldosterone is a hormone that regulates potassium and sodium levels as well as fluid balance in the body thereby maintaining blood volume and blood pressure, helping the body to control stress and maintain a steady metabolic state and normal electrolyte balance.
Secondary hyperaldosteronism is caused by increased adrenal production by medical conditions outside the adrenal gland which stimulates the renin- angiotensin- aldosterone mechanism.