JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

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Bleeding Disorder

Includes

Carriers

Affected Individual
Obligatory	Must not donate if: a) Treated with blood derived coagulation factor concentrates. b) There is a history of excessive bleeding or bruising.
Discretionary	Carrier state: This does not necessarily prevent donation: Refer to a Designated Medical Officer who will liaise with the haematologist that investigated the donor.
See if Relevant	Transfusion
Additional Information	People who have received blood derived coagulation concentrates (these are made from the blood of many hundreds of individual donors) may have been put at risk of infections that can be passed through donations. If someone has had problems with bleeding or bruising taking blood or bone marrow could be harmful. Some people with the carrier state (trait) for some bleeding disorders may be at risk of bleeding themselves.

Family Members, Carers and Sexual Partners of Individuals Treated with Blood Derived Coagulation Factor Concentrates
Obligatory	Must not donate if: a) Treated with blood derived coagulation factor concentrates. b) A sexual partner, or former sexual partner, of a person treated with blood derived coagulation factor concentrates. c) Less than 3 months after the date of an inoculation injury with either blood derived coagulation factor concentrates, or from blood contamination from an affected individual. d) Diagnosed as affected (even mildly) by the disorder.
Discretionary	If 3 months months or more from last sexual contact or inoculation injury, accept.
See if Relevant	Inoculation Injury Transfusion
Additional Information	Blood derived coagulation concentrates: These are made from the blood of many donors. They may put recipients at risk of infections that can be passed through blood. This risk may be shared by their sexual partners. Many bleeding disorders are inherited. Family members that are blood relations may be affected by the bleeding disorder so would be at risk of excessive bleeding or bruising. Most close blood relations would have been screened by a haematologist from whom additional information may be available. Waiting 3 months from the last sexual contact or inoculation injury helps to ensure that the infections tested for by the Blood & Tissues Services will be picked up.
Reason for Change	This entry has been extensively rewritten to improve clarity.

Update Information: This entry was last updated in
TDSG-BM Edition 203, Release 27