Updates to the Red Book
October 2024
Change Notification No. 28 - 2024
- Chapter 5.10 - Adverse Reactions in Donors
- Chapter 5.13 - References
- Chapter 5, Appendix I - Serious Adverse Events of Donation REMOVED
May 2024
Change Notification No. 29 - 2024
- Chapter 7.5.6 - Human Plasma for Fractionation, Leucocyte Depleted
April 2024
Change Notification No. 05 - 2024
- Chapter 21 - Tissue banking: tissue retrieval and processing
- Chapter 7 - Requirements for the timing of testing for Hematopoietic Progenitor Cells (HPCs)
March 2024
Change Notification No. 03 - 2024
- Chapter 2 - Quality in blood and tissue establishments and hospital blood banks
- Chapter 6 - Evaluation and manufacture of blood components
- Chapter 7 - Specifications for blood components
- Annexe 3 - Provisional Components
- Annexe 4 - Redundant Components
- Annexe 5 - Blood Components for Contingency Use
December 2023
Change Notification No. 40 - 2023
November 2023
Change Notification No. 39 - 2023
- Annexe 7 - Requirements for the timing of testing for HPCs
September 2023
Change Notification No. 16 - 2023
- Chapter 4 - Premises and quality assurance at blood donor sessions
- Chapter 5 - Collection of a blood or component donation
- Chapter 11 - Reagent manufacture
- Chapter 12 - Donation testing (red cell immunohaematology)
- Chapter 13 - Patient testing (red cell immunohaematology)
- Chapter 14 - Guidelines for the use of DNA/PCR techniques in Blood Establishments
- Chapter 15 - Molecular typing for red cell antigens
- Chapter 16 - HLA typing and HLA serology
- Chapter 17 - Granulocyte immunology
- Chapter 18 - Platelet immunology
- Chapter 22 - Haemopoietic progenitor cells
- Annexe 7 - Requirements for the timing of testing for HPCs
April 2023
Change Notification No. 22 - 2023
February 2023
Change Notification No. 06 - 2023
- Chapter 9 - Microbiology tests for donors and donations: general specifications for laboratory test procedures
- Chapter 10 - Investigation of suspected transfusion-transmitted infection
- Chapter 19 - Tissue Banking: general principles
- Chapter 20 - Tissue Banking: selection of donors
- Chapter 21 - Tissue Banking: tissue retrieval and processing
- Annexe 6 - Advanced Therapy Medicinal Products (ATMPs)
June 2022
Change Notification No. 33 - 2022
- Chapter 8 - Evaluation of novel blood components, production processes and blood packs: generic protocols
March 2022
Change Notification No. 09 - 2022
- Chapter 7 - Human Plasma for Fractionation Leucocyte Depleted
February 2022
Change Notification No. 10 - 2022
- Annexe 4 - Redundant Components: Convalescent Plasma
Change Notification No. 11 - 2022
- Annexe 3 - Provisional Components: Whole blood, leucocyte depleted, for clinical studies
Change Notification No. 12 - 2022
- Annexe 3 - Provisional Components: Cryoprecipitate pooled, leucocyte depleted, extended shelf life post-thaw
January 2022
Change Notification No. 44 - 2021
- Annexe 5 - Blood Components for Contingency Use
June 2021
Change Notification No.18 - 2021
- Chapter 3 - Care and selection of whole blood and component donors (including donors of pre-deposit autologous blood)
January 2021
Change Notification No. 03 - 2021
- Chapter 21 - Tissue banking: tissue retrieval and processing
November 2020
Change Notification No. 66 - 2020
- Annexe 3 - Provisional Component: Convalescent Plasma (COVID-19), FFP, Leucocyte Depleted
Change Notification No. 67 - 2020
- Annexe 3 - Provisional Component: Convalescent Plasma (COVID-19), FFP, for Neonates and Infants, Leucocyte Depleted
October 2020
Change Notification No. 35 - 2020
- Annexe 3 - Provisional Component: Whole Blood, Leucocyte Depleted for Clinical Studies
August 2020
Change Notification No. 47 - 2020
- Annexe 5 - Platelets, Apheresis, Leucocyte Depleted, at Reduced Dose as a Contingency
June 2020
Change Notification No. 32 - 2020
- Annexe 3 - Provisional Component: Red Cells and Plasma, Leucocyte Depleted
May 2020
Change Notification No. 23 - 2020
- Chapter 7 - Fresh Frozen Plasma for Neonates and Infants, Leucocyte Depleted
Change Notification No. 24 - 2020
- Chapter 7 - Cryoprecipitate for Neonates and Infants, Leucocyte Depleted
Change Notification No. 25 - 2020
- Chapter 7 - Fresh Frozen Plasma, Leucocyte Depleted
Change Notification No. 27 - 2020
April 2020
Change Notification No. 19 - 2020
Change Notification No. 20 - 2020
Change Notification No. 21 - 2020
- Annexe 5 - Blood Components for Contingency Use
Change Notification No. 22 - 2020
- Annexe 5.1 - Red Cells in Additive Solution, Leucocyte Depleted, Extended Shelf Life
November 2019
Change Notification No. 34 - 2019
- Chapter 7 - Platelets in Plasma and Additive Solution for Neonatal Use, Leucocyte Depleted
April 2017
Change Notification No. 10 - 2017
- Chapter 7 - Use of plasma from first time donors
January 2017
Change Notification No. 01 - 2017
- Chapter 11 - General guidelines for reagent red cell manufacture
Change Notification No. 02 - 2017
August 2016
Change Notification No. 32 - 2016
- Chapter 7 - Red Cells, Thawed and Washed, Leucocyte Depleted
Change Notification No. 33 - 2016
- Chapter 7 - Removal of red cells from a controlled temperature environment
Change Notification No. 34 - 2016
- Chapter 7 - Removal of upper limit of pH from Platelet Components
June 2016
Change Notification No. 31 - 2016
May 2016
Change Notification No. 23 - 2016
- Chapter 21 - Tissue banking: Tissue retrieval and processing
April 2016
Change Notification No. 16 - 2016
- Chapter 7 - Fresh Frozen Plasma, Leucocyte Depleted
January 2016
Change Notification No. 12 - 2016
- Chapter 9 - Microbiology tests for donors and donations: general specifications for laboratory test procedures
December 2015
Change Notification No. 18 - 2015
- Chapter 7 - Interruptions to agitation and testing of Platelets, Pooled, Buffy Coat Derived, Leucocyte Depleted and Platelets, Apheresis, Leucocyte Depleted
Change Notification No. 19 - 2015
- Chapter 7 - Platelets in Additive Solution and Plasma, Leucocyte Depleted
Change Notification No. 20 - 2015
- Chapter 6 - Specific gravity of blood components
Change Notification No. 21 - 2015
- Chapter 7 - Leucocyte depletion of blood components - Concessionary release
Change Notification No. 22 - 2015
- Chapter 7 - Concessionary Release Limits for Selected Components
Change Notification No. 23 - 2015
- Chapter 9 - Removal of Chapter 9.4.2. and Figure 9.6 in Chapter 9
Change Notification No. 29 - 2015
- Chapter 25.6 - Table 25.5: Protocol 000001 – blood component dispatch information
Change Notification No. 30 - 2015
- Chapter 7 - Red Cells, Washed, Leucocyte Depleted
January 2015
Change Notification No. 01 - 2015
- Chapter 25.6 - Tables 25.4 and 25.5: Protocol 000001 – blood component dispatch information
June 2014
Change Notification No. 25 - 2014
January 2014
Change Notification No. 15 - 2013
- Chapter 3 - Appendix I: Extra-corporeal volume tables
Change Notification No. 16 - 2013
Errata - Amended pages
- Chapter 7.9.1 - Platelets, Pooled, Buffy Coat Derived, Leucocyte Depleted
- Chapter 7.11.1 - Platelets in Additive Solution and Plasma, Leucocyte Depleted
- Chapter 9.5.3.1 - Single-test system
- Chapter 12.11.2 - Blood and blood components from group O donors with high titres of anti-A, anti-B and/or anti-A,B
- Chapter 7.12.1 - Platelets in Additive Solution, Leucocyte Depleted
Change Notification No. 17 - 2013
Shelf-life (when frozen) of FFP, cryoprecipitate, cryodepleted plasma and MB-treated FFP
- Chapter 7.15 - Fresh Frozen Plasma, Leucocyte Depleted
- Chapter 7.16 - Fresh Frozen Plasma, Methylene Blue Treated and Removed, Leucocyte Depleted
- Chapter 7.17 - Cryoprecipitate, Leucocyte Depleted
- Chapter 7.18 - Cryoprecipitate Pooled, Leucocyte Depleted
- Chapter 7.20 - Plasma, Cryoprecipitate Depleted, Leucocyte Depleted
- Chapter 7.27 - Fresh Frozen Plasma, Neonatal Use, Methylene Blue Treated and Removed, Leucocyte Depleted
- Chapter 7.28 - Cryoprecipitate, Methylene Blue Treated and Removed, Leucocyte Depleted
- Chapter 7.33 - Cryoprecipitate, Pooled, Methylene Blue Treated and Removed, Leucocyte Depleted
June 2013
Change Notification No. 11 - 2013
- Chapter 7.33 - Cryoprecipitate, Pooled, Methylene Blue Treated and Removed, Leucocyte Depleted
Change Notification No. 12 - 2013
- Annexe 3 - Platelets in Additive Solution and Plasma, Leucocyte Depleted, Pathogen-reduced
Last updated 28/10/2024