| Obligatory | Must not donate if: The cardiovascular system is involved. |
| Discretionary | If mild and affecting the locomotor system only, accept. |
| See if Relevant | Disabled Donor Nonsteroidal Anti-Inflammatory Drugs (NSAID) |
| Additional Information | Ankylosing spondylitis can affect the heart valves and the major artery of the body (aorta). Removing blood from the circulation may put the donor at risk of having a heart problem. |
| See | Autoimmune Disease |
| Reason for Change | A link to 'Autoimmune Disease' added. |