| Obligatory | Must not donate if:
1. At any time:
a) Has needed immunosuppression.
b) Dura mater transplanted.
c) Ocular tissue transplanted.
d) Xenotransplant performed.
2. Since January 1st 1980:
Refer to a Designated Medical Officer if the mother has received an allogeneic tissue transplant. |
| Discretionary | a) If an allogeneic tissue or cell transplant was performed before January 1st 1980 and there is no other reason to exclude the donor, accept.
b) If at anytime an autologous tissue, or cells, has been transplanted, accept. |
| See if Relevant | Immunosuppression
Ocular Tissue Recipient
Prion Associated Diseases
Xenotransplantation |
| Additional Information | The transfer of tissues or organs between individuals and species has lead to the spread of infection. The above guidelines are intended to minimize these risks.
There is now a concern that this could also happen with vCJD. This is because in the autumn of 2003 a UK recipient of blood, taken from a healthy donor who later developed vCJD, died from vCJD. Since then there have been several cases of infection with the vCJD prion in recipients of blood from donors who have later developed vCJD.
In view of this, people who have received a tissue or organ transplant since 1980 are now required to have a risk assessment performed. This date is before BSE, which is believed to have caused vCJD, was prevalent. The Designated Medical Officer should consider the availability of alternative donors and discuss the risks and benefits with the physician of the intended recipient. This risk assessment should be shared with the recipient, or their next of kin as appropriate. |
| See | Surgery
Transfusion |
| Reason for Change | To clarify that transplantation of an autologous tissue, or cells, is not a contra-indication to donation, whether or not the tissue, or cells, were stored prior to transplantation. |