JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

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Osteogenesis Imperfecta

Obligatory	Must not donate
Discretionary	Skin Accept for split skin allografts only; not suitable for the preparation of acellular dermal allografts
Additional Information	Osteogenesis Imperfecta is a congenital disorder that results in defective connective tissue due to defects in the genes relating to production of Collagen I or other connective tissue proteins. Pathology includes bones that fracture easily, loose joints, poor muscle tone and thin, discoloured sclera.
Reason for Change	This is a new entry

Update Information: This entry was last updated in
TDSG-LD Edition 203, Release 25