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Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee
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Guidelines for the Blood
Transfusion Services in the UK
Updates
1: Introduction
2. Quality in blood and tissue establishments and hospital blood banks
3: Care and selection of whole blood and component donors (including donors of pre-deposit autologous blood)
4: Premises and quality assurance at blood donor sessions
5: Collection of a blood or component donation
6: Evaluation and manufacture of blood components
7: Specifications for blood components
8: Evaluation of novel blood components, production processes and blood packs: generic protocols
9: Microbiology tests for donors and donations: general specifications for laboratory test procedures
10: Investigation of suspected transfusion-transmitted infection
11: Reagent manufacture
12: Donation testing (red cell immunohaematology)
13: Patient testing (red cell immunohaematology)
14: Guidelines for the use of DNA/PCR techniques in Blood Establishments
15: Molecular typing for red cell antigens
16: HLA typing and HLA serology
17: Granulocyte immunology
18: Platelet immunology
19: Tissue banking: general principles
20: Tissue banking: selection of donors
21: Tissue banking: tissue retrieval and processing
22: Haemopoietic progenitor cells
23: Specification for the uniform labelling of blood, blood components and blood donor samples
24: Specification for the uniform labelling of human tissue products using ISBT 128
25: Standards for electronic data interchange within the UK Blood Transfusion Services
26: Specification for blood pack base labels
27: Specification for labelling consumables used in therapeutic product production
A1: NIBSC standards available from MHRA
A2: ISBT 128 check character calculation
A3: Provisional Components
A4: Redundant Components
A5: Blood Components for Contingency Use
A6: Advanced Therapy Medicinal Products (ATMPs)
A7: Requirements for the timing of testing for HPCs
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Home
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Guidelines for the Blood Transfusion Services
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12.14: Manual testing
Welcome
Updates
1:
Introduction
2:
Quality in blood and tissue establishments and hospital blood banks
3:
Care and selection of whole blood and component donors (including donors of pre-deposit autologous blood)
4:
Premises and quality assurance at blood donor sessions
5:
Collection of a blood or component donation
6:
Evaluation and manufacture of blood components
7:
Specifications for blood components
8:
Evaluation of novel blood components, production processes and blood packs: generic protocols
9:
Microbiology tests for donors and donations: general specifications for laboratory test procedures
10:
Investigation of suspected transfusion-transmitted infection
11:
Reagent manufacture
12:
Donation testing (red cell immunohaematology)
12.1:
Scope
12.2:
General requirements
12.3:
Samples
12.4:
Reagents and test kits
12.5:
Equipment
12.6:
Test procedure
12.7:
Reporting of results
12.8:
Release of tested components
12.9:
Laboratory test categories
12.10:
Mandatory testing of blood donations
12.11:
Additional testing
12.12:
Donations found to have a positive direct antiglobulin test
12.13:
Automated testing
12.14:
Manual testing
13:
Patient testing (red cell immunohaematology)
14:
Guidelines for the use of DNA/PCR techniques in Blood Establishments
15:
Molecular typing for red cell antigens
16:
HLA typing and HLA serology
17:
Granulocyte immunology
18:
Platelet immunology
19:
Tissue banking: general principles
20:
Tissue banking: selection of donors
21:
Tissue banking: tissue retrieval and processing
22:
Haemopoietic progenitor cells
23:
Specification for the uniform labelling of blood, blood components and blood donor samples
24:
Specification for the uniform labelling of human tissue products using ISBT 128
25:
Standards for electronic data interchange within the UK Blood Transfusion Services
26:
Specification for blood pack base labels
27:
Specification for labelling consumables used in therapeutic product production
A1: NIBSC standards available from MHRA
A2: ISBT 128 check character calculation
A3: Provisional Components
A4: Redundant Components
A5: Blood Components for Contingency Use
A6: Advanced Therapy Medicinal Products (ATMPs)
A7: Requirements for the timing of testing for HPCs
Download as PDF
12.14: Manual testing
A manual testing system is one in which the minimum automated testing criteria have not been met.
Manual testing can be used to resolve anomalous results.
Measures should be taken to minimise the testing batch size to avoid the potential for errors.
Manual tests must be performed and controlled according to the manufacturer’s instructions.
Test results must be recorded.
There must be a secure and validated method of entering results onto the host computer. Post result entry verification should be performed.
Last updated 04/09/2023