JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

Anaemia

ObligatoryInform Transplant Centre if:
Cells are from a donor that has an inherited disorder.
Discretionary1. History of anaemia:
This must be assessed regarding its cause, current status and what treatment has been received.

2. Iron deficiency:
a) If not under investigation or on treatment and the underlying cause is not a reason to exclude, accept.

b) Medication to prevent, as opposed to treat, may be acceptable.

3. Other types:
a) Accept or exclude according to the guidelines.

b) In other cases:
Refer to a Designated Medical Officer.
See if RelevantHaemoglobin Disorders
Haemolytic Anaemia
Malignancy

If treated with blood components or products or by plasma exchange or filtration:
Transfusion
Additional InformationA successful transplant will mean the recipient will produce the same blood as the donor. This would be unacceptable for a homozygous (major) form of blood disorder but would probably be acceptable for a heterozygous (minor form, or trait).

By informing the transplant centre, details can be passed on to the person receiving the transplant. This can avoid unnecessary problems in the future. For example searching for the cause of small red cells or anaemia in a person who has had a transplant from a donor with thalassaemia minor (trait).

Donating bone marrow will lower the haemoglobin concentration. People with a history of anaemia may not be able to make up this loss as easily as others.
Giving PBSC by apheresis results in a smaller loss of haemoglobin.

Update Information

This entry was last updated in
TDSG-BM Edition 203, Release 02