Monoclonal antibody therapy and other Biological Modalities

Includes	Systemic treatment with monoclonal antibody (MAb) treatments
Obligatory	Must not donate.
Discretionary	a) If an individual monoclonal antibody treatment is listed in the entry for the underlying condition, apply guidance as per that entry. b) If the underlying condition does not preclude donation, and it is more than 6 months from last treatment, accept.
See	Is there is a specific A-Z index entry for the treatment and/or condition you are concerned about?
See if Relevant	Asthma Autoimmune Disease Clinical Trials Dermatitis Eye Disease Hypercholesterolemia Migraine Osteopenia Psoriasis
Additional Information	The use of monoclonal antibody and other biological therapies continues to expand. Care should be taken to understand the type of treatment and the indication, which may not be included in the ‘See if Relevant’ section. Current scientific literature does not provide conclusive evidence to reject concerns that individuals on these treatments are more prone to infection. Until further clarity is provided in the literature, donors on these medications are withdrawn, unless otherwise stated.
Reason for change	Links to conditions that are currently commonly treated with monoclonal antibody therapies have been added to the ‘See if Relevant’ section, with reference to the expansion in types of treatment and use of these treatments within the ‘Additional Information’ section.

Update Information: This entry was last updated in:
WB-DSG Edition 203 Release 74