CN number: 14 - 2024
CN version: 1
Pre-publication date: 04 July 2024
Release date: 31 July 2024
Implementation date: To be determined by each Service.
This notification includes the following changes:
BM-DSG | CB-DSG | GDRI | TD-DSG | TL-DSG | WB-DSG | Red Book | |
1. Fertility | • | ||||||
2. Accept | • |
Changes are indicated using the key: original text, «inserted text», deleted text.
1. Fertility (revised and renamed entry)
This change applies to the Whole Blood and Components Donor Selection Guidelines
«Fertility» Trying To Conceive
Obligatory | Must not donate if:
|
Discretionary |
|
See if Relevant | Prion Associated Diseases «Surgery» |
Additional Information | The use of human gonadotrophin of pituitary origin (follicle-stimulating hormone (FSH) and luteinizing hormone (LH)) had stopped in the UK by 1986. The situation in other countries varied so specific dates cannot be given. Metrodin HP® was withdrawn by the Committee on Safety of Medicines in 2003 and following advice from the Medicines and Healthcare products Regulatory Agency the precautionary principle has been applied to withdraw donors who have been treated with this product. Donors treated for infertility after 2003 in the UK will not have been treated with this product. «There is no need to confirm that the donor was not treated with Metrodin HP®. Donors may have received other non-pituitary derived gonadotrophins which are acceptable.» «Recipients of donated eggs, embryos and sperm are eligible to donate. This is in accordance with the SaBTO Microbiological Safety Guidelines. Donors who have undergone egg donation, egg collection for fertility preservation, and surgical sperm retrieval should be assessed regarding any hormone treatment they have received and using the Surgery entry. Fertility preservation is available for:
Reasons that donors may be undergoing treatments and procedures for fertility include Polycystic Ovary Syndrome (PCOS), Endometriosis, testicular problems, genetic conditions. For one in four individuals the cause of their fertility problems may not be known. Sensitive questioning may be needed to establish any underlying cause or associations that may be relevant to the donor’s health and eligibility. Donors with inherited conditions e.g. mitochondrial disease may undergo fertility-related diagnostic and assistance treatments and procedures. Unaffected carriers may be eligible to donate if they otherwise fulfil the criteria.» |
Reason for Change | «The eligibility of recipients of donated eggs or embryos is now specified. Inclusion of criteria and additional information regarding any underlying or associated conditions. Replacement of reference to specific drugs with criteria to preclude donation whilst being monitored for pregnancy. Addition of link to Surgery entry to facilitate assessment of donors who have had fertility-related procedures. Inclusion of additional information for donors who have had a fertility-related procedure not due to a primary fertility problem.» |
Donor Information | If you wish to obtain more information regarding a personal medical issue, please contact your National Help Line. Please do not contact this web site for personal medical queries, as we are not in a position to provide individual answers. |
2. Accept (revised entry)
This change applies to the Whole Blood and Components Donor Selection Guidelines
Accept
(applies to female donors only)
Discretionary | If use of medicines or other therapies are not a reason to defer, accept. |
See if Relevant | Complementary Therapy Drug Index - preparations which affect platelet function «Fertility» Nonsteroidal Anti-Inflammatory Drugs Neurosurgery If taking Dopamine-receptor agonists (e.g. Rotigotine, Bromocriptine, Ropinirole, Pramipexole), see: Central Nervous System Disease. |
Additional Information | The condition that brought you to this entry is not a reason for deferral. It is however important to ensure that there are no other factors that may affect any donation, such as having symptoms related to hypotension as side effects from the use of medicines such as dopamine receptor agonist drugs (e.g. rotigotine, bromocriptine, ropinirole and pramipexole) that can cause hypotension and fainting, or complementary (alternative) therapy. |
Reason for Change | «Fertility has been added to See if Relevant section.» |
Donor Information | If you wish to obtain more information regarding a personal medical issue, please contact your National Help Line. Please do not contact this web site for personal medical queries, as we are not in a position to provide individual answers. |
The following redirection will be added to the A-Z index:
PCOS » Accept