SRI Publications

The Systematic Review Initiative has so far completed over 120 systematic reviews covering many different aspects of transfusion medicine, including transfusion and COVID-19. Our reviews are all produced using strict methodological criteria in accordance with best evidence-based practice, and have been published in a wide variety of journals, with approximately half appearing in The Cochrane Library. Please view our Publications pages via the left-hand menu for full details of our reviews with full text links.

Recently completed systematic reviews include:

• Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery
• Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery
• Do treatments for anaemia improve tje quality of life and physical function in patients with myelodysplastic syndromes?
• Interventions for chronic kidney disease in people with sickle cell disease
• Definitions of massive transfusion in adults with critical bleeding
• Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery
• Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia
• Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic and long bone fractures
• Convalescent plasma or immunoglobulin treatment for people with severe respiratory viral infections due to coronaviruses or influenza
• Clinical prediction models for blood transfusion in patients undergoing elective surgery
• Hyperkalaemia following blood transfusion - a systematic review assessing evidence and risks
• Assessing the risks of haemolysis as an adverse reaction following the transfusion of ABO incompatible plasma-containing components
• Convalescent plasma or hyperimmune immunoglobulin for people with COVID‐19
• Efficacy and safety of intravenous iron therapy for treating anaemia in critically ill adults (rapid review)
• Difference in potential harms between whole blood and component blood transfusion in major bleeding (rapid review)