JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

Red Cell Transfusion

  • Radford M, Estcourt LJ, Sirotich E, Pitre T, Britto J, Watson M, Brunskill SJ, Fergusson DA, Dorée C, Arnold DM.
    Restrictive versus liberal red blood cell transfusion strategies for people with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem cell support.
    The Cochrane Database of Systematic Reviews 2024;5:CD011305.
    Access abstract: PubMed / full text: PubMed Central (freely available)

  • Lloyd TD, Geneen LJ, Bernhardt K, McClune W, Fernquest SJ, Brown T, Dorée C, Brunskill SJ, Murphy MF, Palmer AJ.
    Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery.
    The Cochrane Database of Systematic Reviews 2023;9:CD001888.
    Access abstract: PubMed / full text: PubMed Central (freely available)

  • Roy NB, Carpenter A, Dale-Harris I, Dorée C, Estcourt LJ.
    Interventions for chronic kidney disease in people with sickle cell disease.
    The Cochrane Database of Systematic Reviews 2023;8:CD012380.
    Access abstract: PubMed / full text: Wiley (freely available)

  • Carson JL, Stanworth SJ, Dennis JA, Trivella M, Roubinian N, Fergusson DA, et al.
    Transfusion thresholds for guiding red blood cell transfusion.
    The Cochrane Database of Systematic Reviews 2021;12:CD002042.
    Access abstract: PubMed / full text: PubMed Central (freely available)

  • Estcourt LJ, Kohli R, Hopewell S, Trivella M, Wang WC.
    Blood transfusion for preventing primary and secondary stroke in people with sickle cell disease.
    The Cochrane Database of Systematic Reviews 2020;7:CD003146.
    Access abstract: PubMed / full text: PubMed Central (freely available)

  • Stanworth SJ, New HV, Apelseth TO, Brunskill S, Cardigan R, Doree C, Germain M, Goldman M, Massey E, Prati D, Shehata N, So-Osman C, Thachil J.
    Effects of the COVID-19 pandemic on supply and use of blood for transfusion.
    Lancet Haematology 2020;7(10):e756-e764.
    Access abstract: PubMed / full text: Elsevier (freely available)

  • Estcourt LJ, Kimber C, Trivella M, Doree C, Hopewell S. 
    Preoperative blood transfusions for sickle cell disease. 
    The Cochrane Database of Systematic Reviews 2020;7:CD003149.
    Access abstract: PubMed / full text: Wiley (subscription may be required)

  • Estcourt LJ, Kimber C, Hopewell S, Trivella M, Doree C, Abboud MR.
    Interventions for preventing silent cerebral infarcts in people with sickle cell disease.
    The Cochrane Database of Systematic Reviews 2020;4:CD012389.
    Access abstract: PubMed / full text: Wiley (subscription may be required)

  • Trivella M, Stanworth SJ, Brunskill S, Dutton P, Altman DG.
    Can we be certain that storage duration of transfused red blood cells does not affect patient outcomes?
    BMJ 2019; 365 :l2320.
    Access abstract: PubMed / full text: BMJ (subscription required)

  • Estcourt LJ, Hopewell S, Trivella M, Hambleton IR, Cho G.
    Regular long-term red blood cell transfusions for managing chronic chest complications in sickle cell disease.
    The Cochrane Database of Systematic Reviews. 2019;10:CD008360.
    Access abstract: PubMed / full text: PubMed Central (freely available)

  • Shah A, Brunskill SJ, Desborough MJ, Doree C, Trivella M, Stanworth SJ.
    Transfusion of red blood cells stored for shorter versus longer duration for all conditions.
    The Cochrane Database of Systematic Reviews 2018;12:CD010801.
    Access abstract: PubMed / full text: Wiley (subscription may be required)

  • Fortin PM, Hopewell S, Estcourt LJ.
    Red blood cell transfusion to treat or prevent complications in sickle cell disease: an overview of Cochrane reviews.
    The Cochrane Database of Systematic Reviews 2018;(8): CD012082.
    Access abstract: PubMed / full text: Wiley (subscription may be required)

  • Carson JL, Stanworth SJ, Alexander JH, Roubinian N, Fergusson DA, Triulzi DJ, Goodman SG, Rao SV, Doree C, Hebert PC.
    Clinical trials evaluating red blood cell transfusion thresholds: an updated systematic review and with additional focus on patients with cardiovascular disease.
    American Heart Journal 2018; 200:96-101.
    Access abstract: PubMed / full text: Science Direct (subscription may be required)

  • Odutayo A, Desborough MJ, Trivella M, Stanley AJ, Doree C, Collins GS, Hopewell S, Brunskill SJ, Kahan BC, Logan RF, Barkun AN, Murphy MF, Jairath V.
    Restrictive versus liberal blood transfusion for gastrointestinal bleeding: a systematic review and meta-analysis of randomised controlled trials.
    The Lancet Gastroenterology & Hepatology 2017; 2(5):354-60.
    Access abstract: PubMed / full text: Science Direct (subscription may be required)

  • Desborough MJR, Colman KS, Prick BW, Duvekot JJ, Sweeney C, Odutayo A, Jairath V, Doree C, Trivella M, Hopewell S, Estcourt LJ, Stanworth SJ.
    Effect of restrictive versus liberal red cell transfusion strategies on haemostasis: systematic review and meta-analysis.
    Thrombosis and Haemostasis 2017; 117(5):889-98.
    Access abstract: PubMed / full text: Thieme (subscription may be required)

  • Estcourt LJ, Fortin PM, Hopewell S, Trivella M, Wang WC.
    Blood transfusion for preventing primary and secondary stroke in people with sickle cell disease. 
    Cochrane Database of Systematic Reviews 2017;(1): CD003146.
    Access abstract: PubMed / full text: Wiley (subscription may be required)

  • Keir A, Pal S, Trivella M, Lieberman L, Callum J, Shehata N, Stanworth SJ.
    Adverse effects of red blood cell transfusions in neonates: a systematic review and meta-analysis.
    Transfusion 2016; 56(11):2773–2780.
    Access abstract: PubMed / full text: Wiley (subscription may be required)

  • Shah A, McKechnie S, Brunskill SJ, Stanworth SJ. 
    Fresh versus old red cell transfusions: what have the recent clinical trials found?
    Current Opinion in Hematology 2016; 23(6):550-556.
    Access abstract: PubMed / full text: Wolters Kluwer (subscription required)

  • Estcourt LJ, Fortin PM, Trivella M, Hopewell S.
    Preoperative blood transfusions for sickle cell disease.
    Cochrane Database of Systematic Reviews 2016;(4):CD003149.
    Access abstract: PubMed / full text: Wiley (subscription may be required)

  • Estcourt LJ, Fortin PM, Hopewell S, Trivella M, Hambleton IR, Cho G.
    Regular long-term red blood cell transfusions for managing chronic chest complications in sickle cell disease.
    Cochrane Database of Systematic Reviews 2016;(5):CD008360.
    Access abstract: PubMed / full text: Wiley (subscription may be required)

  • Docherty AB, O'Donnell R, Brunskill S, Trivella M, Doree C, Holst L, Parker M, Gregersen M, Pinheiro de Almeida J, Walsh TS, Stanworth SJ.
    Effect of restrictive versus liberal transfusion strategies on outcomes in patients with cardiovascular disease in a non-cardiac surgery setting: systematic review and meta-analysis.
    BMJ 2016;352:i1351.
    Access abstract: PubMed / full text: PMC (freely available)

  • Gu Y, Estcourt LJ, Doree C, Hopewell S, Vyas P.
    Comparison of a restrictive versus liberal red cell transfusion policy for patients with myelodysplasia, aplastic anaemia, and other congenital bone marrow failure disorders.
    Cochrane Database of Systematic Reviews 2015; (10): CD011577.
    Access abstract: PubMed / full text: PMC (freely available)

  • Brunskill SJ, Wilkinson KL, Doree C, Trivella M, Stanworth S.
    Transfusion of fresher versus older red blood cells for all conditions.
    Cochrane Database of Systematic Reviews 2015; (5): CD010801.
    Access abstract: PubMed / full text: Wiley (subscription may be required)

  • Brunskill SJ, Millette SL, Shokoohi A, Pulford EC, Doree C, Murphy MF, Stanworth S.
    Red blood cell transfusion for people undergoing hip fracture surgery.
    Cochrane Database of Systematic Reviews 2015; (4): CD009699.
    Access abstract: PubMed / full text: Wiley (subscription may be required)

  • Butler C, Tay J, Doree C, Brunskill SJ, Trivella M, Fergusson DA, Tinmouth A, Murphy MF.
    Restrictive versus liberal red blood cell transfusion strateiges for patients with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem cell support (protocol).
    Cochrane Database of Systematic Reviews 2014; (9): CD011305.
    Access abstract: PubMed / full text: Wiley (subscription may be required)

  • Wilkinson KL, Brunskill SJ, Doree C, Trivella M, Gill R, Murphy MF.
    Red cell transfusion management for patients undergoing cardiac surgery for congenital heart disease.
    Cochrane Database of Systematic Reviews 2014; (2): CD009752.
    Access abstract: PubMed / full text: Wiley (subscription may be required)

  • Hopewell S, Omar O, Hyde C, Yu L-M, Doree C, Murphy M.
    A systematic review of the effect of red blood cell transfusion on mortality: evidence from large scall observational studies published between 2006 and 2010.
    BMJ Open 2013; 3:e002154.
    PMID: 23645909.  doi: 10.1136/bmjopen-2012-002154.
    Access abstract: PubMed / full text: BMJ Open (freely available)

  • Wilkinson KL, Brunskill SJ, Dorée C, Hopewell S, Stanworth S, Murphy MF, Hyde C.
    The clinical effects of red blood cell transfusions: an overview of the randomized controlled trials evidence base.
    Transfusion Medicine Reviews 2011; 25(2):145-155.e2.
    Access abstract: PubMed / full text: ScienceDirect (subscription required)  
     
  • Jairath V, Hearnshaw S, Brunskill SJ, Doree C, Hopewell S, Hyde C, Travis S, Murphy MF..
    Red cell transfusion for the management of upper gastrointestinal haemorrhage.
    Cochrane Database of Systematic Reviews 2010; (9):CD006613.
    Access abstract: PubMed / full text: Wiley (subscription may be required)
     
  • Pinchon DJ, Stanworth SJ, Dorée C, Brunskill S, Norfolk DR.
    Quality of life and use of red cell transfusion in patients with myelodysplastic syndromes. A systematic review.
    American Journal of Hematology 2009; 84(10): 671-7.
    Access abstract: PubMed / full text: Wiley (subscription required) 
     
  • Wilkinson KL, Brunskill SJ, Doree CJ, Murphy MF, Hyde CJ.
    The clinical effectiveness of blood and red cell transfusion.
    Transfusion Medicine 2009; 19(s1):20. Abstract PO2.
    Access abstract: Wiley (subscription required)