JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee
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Management of Bleeding

  • Gibbs VN, Champaneria R, Sandercock J, Welton NJ, Geneen LJ, Brunskill SJ, Dorée C, Kimber C, Palmer AJ, Estcourt LJ.
    Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a systematic review and network meta-analysis.
    The Cochrane Database of Systematic Reviews. 2024;1: CD013295.
    Access abstract: PubMed / full text: PubMed Central (freely available)

  • Beverly A, Ong G, Kimber C, Sandercock J, Doree C, Welton NJ, Wicks P, Estcourt LJ.
    Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery: a systematic review and network meta-analysis.
    The Cochrane Database of Systematic Reviews. 2023;2:CD013649.
    Access abstract: PubMed / full text: PubMed Central (freely available)

  • Gibbs VN, Champaneria R, Geneen LJ, Raval P, Doree C, Brunskill SJ, Novak A, Palmer AJ, Estcourt LJ.
    Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic and long bone fractures.
    The Cochrane Database of Systematic Reviews. 2023;6:CD013499.
    Access abstract: PubMed / full text: PubMed Central (freely available)

  • McQuilten ZK, Crighton G, Brunskill S, Morison JK, Richter TH, Waters N, et al.
    Optimal Dose, Timing and Ratio of Blood Products in Massive Transfusion: Results from a Systematic Review.
    Transfusion Medicine Reviews 2018; 32(1):6-15.
    Access abstract: PubMed / full text: ScienceDirect (subscription required)

  • Fabes J, Brunskill SJ, Curry N, Doree C, Stanworth SJ.
    Pro-coagulant haemostatic factors for the prevention and treatment of bleeding in people without haemophilia.
    Cochrane Database of Systematic Reviews 2018;12:CD010649.
    Access abstract: PubMed / full text: PubMed Central (freely available)

  • Oakland K, Isherwood J, Lahiff C, Goldsmith P, Desborough M, Colman KS, Guy R, Uberoi R, Murphy MF, East JE, Hopewell S, Jairath V.
    Diagnostic and therapeutic treatment modalities for acute lower gastrointestinal bleeding: a systematic review.
    Endoscopy International Open. 2017;5(10):E959-E973.
    Access abstract: PubMed / full text: PubMed Central (freely available) 

  • Murphy MF, Estcourt LJ, Goodnough LT.
    Blood transfusion strategies in elderly patients. [Letter]
    Lancet Haematology 2017;4(10):e453-e454
    Access abstract: PubMed / full text: ScienceDirect (subscription required) 

  • Desborough MJ, Oakland K, Brierley C, Bennett S, Doree C, Trivella M, Hopewell S, Stanworth SJ, Estcourt LJ.
    Desmopressin use for minimising perioperative blood transfusion.
    Cochrane Database of Systematic Reviews 2017;7:CD001884.
    Access abstract: PubMed / full text: PubMed Central (freely available)

  • Desborough MJ, Oakland KA, Ladoni G, Crivellari, Doree C, Estcourt LJ, Stanworth SJ.
    Desmopressin for treatment of platelet dysfunction and reversal of antiplatelet agents: a systematic review and meta-analysis of randomised controlled trials.
    Journal of Thrombosis and Hemostasis 2017. 15(2):263-272.
    Access abstract: PubMed / full text: Wiley (subscription required)

  • Estcourt LJ, Desborough M, Brunskill SJ, Doree C, Hopewell S, Murphy MF, Stanworth SJ.
    Antifibrinolytics (lysine analogues) for the prevention of bleeding in people with haematological disorders.
    Cochrane Database of Systematic Reviews 2016;(3):CD009733.
    Access abstract: PubMed / full text: PubMed Central (freely available)

  • McQuilten ZK, Crighton G, Engelbrecht S, Gotmaker R, Brunskill SJ, Murphy MF, Wood EM.
    Transfusion interventions in critical bleeding requiring massive transfusion: a systematic review
    Transfusion Medicine Reviews 2015; 29(2):127-37.
    Access abstract: PubMed / full text: ScienceDirect (subscription required) 

  • Hunt H, Stanworth S, Curry N, Woolley T, Cooper C, Ukoumunne O, Zhelev Z, Hyde C.
    Thromboelastography (TEG) and rotational thromboelastometry (ROTEM) for trauma induced coagulopathy in adult trauma patients with bleeding
    Cochrane Database of Systematic Reviews 2015; (2):CD010438.
    Access abstract: PubMed / full text: PubMed Central (freely available) 

  • Estcourt LJ, Pinchon D, Symington E, Kelly AM, Doree C, Brunskill S, Glidewell L, Stanworth S.
    Does bleeding affect patient-reported outcome measures in patients with myelodysplasia or hematologic malignancies: a systematic review.
    Transfusion 2014;(54): 1166–1179.
    Access abstract: PubMed / full text: Wiley (subscription required) 

  • Curry N, Hopewell S, Dorée C, Hyde C, Brohi K, Stanworth S.
    The acute management of trauma hemorrhage: a systematic review of randomized controlled trials.
    Critical Care 2011;1 5(2): R92.
    Access abstract: PubMed / full text: BioMed Central (freely available)
     
  • Curry N, Stanworth S, Hopewell S, Dorée C, Brohi K, Hyde C.
    Trauma-induced coagulopathy - a review of the systematic reviews: is there sufficient evidence to guide clinical transfusion practice?
    Transfusion Medicine Reviews 2011; 25(3): 217-231.e2.
    Access abstract: PubMed / full text: ScienceDirect (subscription required) 
     
  • Hearnshaw S, Travis S, Murphy M.
    The role of blood transfusion in the management of upper and lower intestinal tract bleeding.
    Best Practice & Research Clinical Gastroenterology 2008; 22(2):355-371.
    Access abstract: PubMed / full text: ScienceDirect (subscription required)