Immunoglobulin Therapy

Must not donate if:
a ) Immunosuppressed.

b) Donors with recovered immunodeficiency:
Refer to a Designated Clinical Support Officer.

a) If the intravenous or subcutaneous human immunoglobulin was given before 1980, accept.

b) Routine ante- and post- natal use of anti-D immunoglobulin, accept.

c) If single dose prophylactic immunoglobulin has been given, accept.

d) If treated with intravenous immunoglobulins after 1st January 1999: if underlying condition is not a contraindication, accept. Refer to designated clinical support officer if further advice required.

Hepatitis A
Hepatitis B
Rabies
Tetanus Immunization

Immunoglobulin used before 1980 is unlikely to be affected by vCJD.

Single dose immunoglobulin is unlikely to pose a significant risk for transmitting vCJD.

Since 1999, intravenous immunoglobulins prepared from UK donors have no longer been used, as a risk reduction measure for vCJD transmission.

If treated with intravenous or subcutaneous human immunoglobulin:
Transfusion

To permit donation from donors who have received intravenous immunoglobulin after 1st January 1999, if the reason for treatment is not a contraindication.