| Discretionary | a) If an autologous tissue, or cells, has been transplanted at any time, and there is no other reason to exclude the donor, accept.
b) If an allogeneic tissue (except dura mater or ocular tissue) or cell transplant was performed before 1st January 1980, and there is no other reason to exclude the donor, accept.
c) For donations of heart valves, skin, ocular tissue and pancreatic islets only: If an allogeneic tissue (except dura mater or ocular tissue), or cells, has been transplanted at any time, and there is no other reason to exclude the donor, accept.
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| Additional Information | The transfer of tissues or cells between individuals and species has led to the spread of infection. The above guidelines are intended to minimise these risks.
People who have received a tissue or cell transplant since 1980 are excluded from donation of any tissues except for heart valves, ocular tissue, pancreatic islets and skin as a precautionary measure against the risk of transmission of vCJD in the same way as recipients of transfusion are.
Dura mater and ocular tissue allografts have been implicated in iatrogenic CJD. Iatrogenic CJD refers to the transmission of prions via inadvertent medical exposure. Recipients of dura mater and ocular tissue recipients are excluded.
Dura mater use stopped in the UK by 1993. The situation in other countries varied so specific dates cannot be given.
Tissue allograft recipients do not require immunosuppression. If the recipient was on immunosuppression for any other reason, see Immunosuppression entry.
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