JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

HTLV

1. Affected Individual
Obligatory

Must not donate.

See if Relevant

Blood Safety Entry

Additional Information

HTLV (Human T Cell Lymphotropic Virus I and II) infection can cause serious blood and nervous system disease. It is known to be transmitted by transfusion. In the early stages of infection the testing used by the Blood Services may not detect the virus allowing it to be passed on by transfusion.

Information

This is a requirement of the Blood Safety and Quality Regulations 2005.

Reason for change

See below

2. Current or Former Sexual Partner of Affected Individual
Obligatory

Must not donate 

Discretionary

1. If it is more than three months since last sexual contact and a validated test for anti-HTLV antibodies is to be undertaken on the donated component(s), accept
2. If it is more than three months since last sexual contact, the donor has been previously tested for anti-HTLV antibodies by the blood service and this test was performed at least three months after the last sexual contact, accept
 

See if Relevant

Blood Safety Entry

Additional Information

HTLV infection can be spread through sexual activity. It may however not be transmitted for a long time into a relationship. This could be because the infection becomes more active in the infected partner, the uninfected partner acquires another infection or an injury to a mucous membrane, or there is a change in the use of, or failure of, barrier contraceptives (condoms etc.). In the early stages of infection the testing used by the Blood Services may not detect the virus allowing it to be passed on by transfusion.
Waiting three months from the last sexual contact will ensure that any infection is picked up by the tests used by the Blood Services.
Blood services in the UK are not required to test all donations for anti-HTLV antibodies. Blood services will need to identify at risk donors at health screening and consider options for discretionary HTLV testing. Otherwise, donors who report sexual contact with an affected individual must be deferred.
 

Information

This is a requirement of the Blood Safety and Quality Regulations 2005.

Reason for change

See below 

3. Person Currently or Formerly Sharing a Home with an Affected Individual
Discretionary

Accept.

See if Relevant

2. Current or Former Sexual Partner of Affected Individual above.

Additional Information

HTLV is neither contagious nor spread by the faecal-oral route. It is usually only spread through a direct blood to blood or sexual route. For these reasons household contacts do not need to be deferred.

Reason for change

See below

Reason for change

This entry was updated to remove the reference to a separate entry for Northern Ireland. This is to reflect changes in donor selection criteria for donors in Northern Ireland (1st June 2020) which are in line with the other UK Blood Services and the SaBTO Donor Selection Criteria Review Report (2017).

Donor Information

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Update Information

This entry was last updated in:
DSG-WB Edition 203, Release 50